I like sealing the bags with these clips because it looks better than zip ties....however I am an average size woman and the pliers have to be opened all the way to put a larger clip in and then it is really difficult to hold bag closed with one hand and squeeze these shut with the other....I finally got someone to help and then it works good. But I found that I had to very carefully push against the twisted neck of the bag and with very steady hands squeeze the pliers shut....not as easy as I figured is all. On some of the larger turkeys I found that even with a nice squeeze and closure, air came back in the bag....may be a novice issue, so hopefully with practice it will improve..